Latest CKD Research Topics

Stay up to date with the most important advances in chronic kidney disease (CKD) research, clinical trials, and patient resources. Explore our clinical trials directory and learn about new biomarkers for better CKD monitoring.

Updated for 2024–2025

CKD Research Timeline

Understanding the timeline of CKD research helps you appreciate how far we've come and what breakthroughs might be on the horizon for kidney disease treatment.

Featured Research Topics

💊Treatment

SGLT2 Inhibitors Beyond Diabetes

Clinical trials show that SGLT2 inhibitors slow CKD progression even in non-diabetics.

Key medications: Dapagliflozin, Empagliflozin
2024-2025
2 studies
🦠Prevention

Gut Microbiome and CKD

Studies show imbalance in gut bacteria increases uremic toxins.

Interventions: fiber-rich diets, probiotics, fecal transplants (early-stage research)
2024-2025
1 study
🥗Nutrition

Low-Protein Diet + Ketoanalogues

New interest in very low protein diets combined with ketoacid supplements to delay dialysis.

Randomized trials underway in Europe and Asia
2024-2025
2 studies
🔬Diagnosis

Novel Biomarkers for Early Detection

TNFR1, TNFR2, and KIM-1 outperform creatinine in predicting rapid decline.

Goal: personalized kidney disease staging
2024-2025
1 study
🌱Nutrition

Plant-Based Diets and CKD Outcomes

Observational studies link vegetarian diets with slower CKD progression and lower cardiovascular risk.

Long-term dietary impact studies
2024-2025
1 study
⚖️Treatment

Potassium-Reducing Therapies

Patiromer and sodium zirconium cyclosilicate allow patients to continue RAAS inhibitors safely.

New medication options for hyperkalemia
2024-2025
2 studies
🤖Technology

AI in Kidney Risk Prediction

Machine learning models increasingly used to forecast progression, hospitalizations, and medication response.

Predictive analytics for personalized care
2024-2025
1 study
🦠Epidemiology

CKD and COVID-19 Impact

Long-term kidney complications after COVID-19 infection under review.

Research on risk of acute kidney injury (AKI) leading to long-term CKD
2024-2025
1 study

Tips for Staying Updated

Subscribe to JASN Alerts or Kidney International eTOC for monthly updates.

Follow @NephJC and @KidneyNews on Twitter/X for live study reviews.

Ask your doctor about relevant clinical trials in your area using ClinicalTrials.gov.

Read KDIGO guidelines every few years for best practice standards.